![]() ![]() This study went on for 3 months, and the participants took 300 mg, 3 times per day. The participants also lost 3.6% of their body fat ( 14).Īnother more impressive study was conducted in 37 men and women with metabolic syndrome. In a 12-week study in obese individuals, 500 mg taken three times per day caused about 5 pounds of weight loss, on average. So far, two studies have examined the effects on body weight. It works as well as some pharmaceutical drugs.īerberine may also be effective as a weight loss supplement. Bottom Line: Berberine is very effective at lowering blood sugar and HbA1c, which are elevated in people with diabetes. This stuff really works, in both the studies and the real world. If you look at discussions online, you often see people with sky-high blood sugars literally normalizing them just by taking this supplement. It works very well with lifestyle modifications, and also has additive effects when administered with other blood sugar lowering drugs ( 2). It also lowered hemoglobin A1c by 12% (a marker for long-term blood sugar levels), and also improved blood lipids like cholesterol and triglycerides ( 12).Īccording to a big review of 14 studies, berberine is as effective as oral diabetes drugs, including metformin, glipizide and rosiglitazone ( 13). In one study of 116 diabetic patients, 1 gram of berberine per day lowered fasting blood sugar by 20%, from 7.0 to 5.6 mmol/L (126 to 101 mg/dL), or from diabetic to normal levels ( 12).
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